Interleukin 12 p40 subunit (IL-12p40) (Uniprot A0A8U0MDC4) is a component of the bioactive cytokines IL-12 and IL-23. Existing in either a monomeric or homodimeric form it is induced in excess of the other subunits of IL-12 and IL-23. Most known for providing negative feedback by competing for the IL-12 receptor it also functions as a chemoattractant for macrophages and is associated with several pathogenic inflammatory responses.
| Description | |
| Source | HEK293, Met1-Ser329, with C-terminal His Tag |
| Purity | >99% by SDS-PAGE |
| Predicted Molecular Mass | 39.1 kDa |
| SDS-PAGE | 41.7 kDa |
| Applications | ELISA, WB |
| Formulation | Lyophilized from 1X PBS with Trehalose |
| Preparation and Storage | |
| Reconstitution | Reconstitute at 25μg/mL in sterile PBS containing at least 0.1% protein |
| Shipping | Ambient |
| Storage | 5 years at -80°C; 2 years at -20°C or 4°C Upon reconstitution: 5 years at -80°C; 2 years at -20°C |
