Human Gelsolin (UnitProt # P06396) is a potent calcium regulated actin filament severing protein that works to disassemble and reorganize the actin network. The extracellular isoform, plasma gelsolin, is suggested to act as an actin scavenging protein. Decreased levels of plasma gelsolin have been reported in trauma, burns, rheumatoid arthritis, and alzheimer disease.
|Source||E. Coli (ala28-ala782) with His Tag|
|Purity||>95% by SDS-PAGE|
|Formulation||Lyophilized from 1X PBS with Trelahose|
|Preparation and Storage|
|Reconstitution||Reconstitute at 50 μg/mL in sterile PBS containing at least 0.1% protein|
|Storage||5 years at -80°C; 2 years at -20°C or 4°C|
Upon reconstitution: 5 years at -80°C; 2 years at -20°C