Interleukin-2 (IL-2; UniProt #B3VBJ5) is a cytokine signaling molecule that regulates white blood cells. It is produced primarily by T cells after activation by an antigen. IL-2 signals through the IL-2 receptor which leads to the activation of at least 2 major signaling pathways which mediate cell growth, survival, activation induced cell death and differentiation. A pro-inflammatory cytokine, IL-2 activates T cells to produce TNFα as well as IFNγ and controls immune response by contributing to the development of regulatory T cells. Therefore IL-2 plays an important role in antigen specific immune responses
| Description | |
| Source | HEK293, Met1-Gln155, with C-terminal His Tag |
| Purity | >99% by SDS-PAGE |
| Predicted Molecular Mass | 17.6 kDa |
| SDS-PAGE | 17.6kDa |
| Applications | ELISA, WB |
| Formulation | Lyophilized from 1X PBS with Trehalose |
| Preparation and Storage | |
| Reconstitution | Reconstitute at 25μg/mL in sterile PBS containing at least 0.1% protein |
| Shipping | Ambient |
| Storage | 5 years at -80°C; 2 years at -20°C or 4°C Upon reconstitution: 5 years at -80°C; 2 years at -20°C |
