Interleukin 6 (IL-6; UniProt #A0A1U7QW01) is a soluble cytokine that can effect inflammation, immune response, and hematopoiesis. IL-6 signals through IL-6R, which can occur as a transmembrane or a soluble receptor that is found in serum. IL-6 is generated immediately following environmental stresses such as infections and tissue injuries. Dysregulation of IL-6, which can lead to over production, may contribute to chronic inflammation and autoimmunity.
|Source||HEK293, Met1-Asn212, with C-terminal His Tag|
|Purity||>95% by SDS-PAGE|
|Formulation||Lyophilized from 1X PBS with Trehalose|
|Preparation and Storage|
|Reconstitution||Reconstitute at 25μg/mL in sterile PBS containing at least 0.1% protein|
|Storage||5 years at -80°C; 2 years at -20°C or 4°C|
Upon reconstitution: 5 years at -80°C; 2 years at -20°C