Interferon gamma (IFNγ) is a dimerized soluble cytokine that is predominately produced by natural killer and natural killer T cells during the innate immune response and by T cells once antigen specific immunity develops. IFNγ is crucial for immunity against intracellular pathogens and for tumor control. Release of IFNγ is controlled mostly by the cytokines IL-12 and IL-18. Serum IFNγ levels have been shown to be elevated in active cases of systemic lupus erythematosus (SLE) and may be associated with the development of autoimmune diseases like SLE.
| Description | |
|---|---|
| Immunogen | HEK293-derived recombinant Golden Hamster IFNγ. Gln24-Ile174. |
| Reactivity | Hamster |
| Source | Mouse monoclonal IgG1 |
| Purification | Protein G purified from hybridoma cell culture supernatant |
| Applications | ELISA (Capture) |
| Formulation | Lyophilized from PBS with Trelahose Reconstitute in 100μL ddH20 to 1 mg/mL |
| Shipping | Ambient |
| Storage | 5 years at -20°C to -80°C as supplied 1 month at 4°C after reconstitution with preservative 1 year at -20°C to -80°C after reconstitution |
| Expiration | See lot specific CoA |
 | Hamster IFNγ Luminex Assay Capture: Hamster IFNγ clone HMG-1C1 (Cat # M2037) |
