IL-4, ham mAb (HM4-1C6)

$325.00

icon_pdf

CAT #: M2035

Interleukin 4 (IL-4) is a cytokine that that functions as a potent regulator of immunity. It is secreted primarily by mast cells, Th2 cells, eosinophils, and basophils. IL-4 signals through the IL-4R α-chain which activates several pathways. This activation can lead to B cell proliferation, survival of T and B cells and chemokine production. IL-4 has been shown to have a role in allergic asthma through its regulation of TH2 cell proliferation and IgE synthesis, and atopy or excessive IgE production has been associated with elevated levels of IL-4 in response to allergens.

Description
Immunogen
HEK293-derived recombinant Golden Hamster IL-4. Asn20-Phe147.
Reactivity
Hamster
Source
Mouse monoclonal IgG1
Purification
Protein G purified from hybridoma cell culture supernatant
Applications
ELISA (Capture)
Formulation
Lyophilized from PBS with Trelahose
Reconstitute in 100μL ddH20 to 1 mg/mL
Shipping
Ambient
Storage
5 years at -20°C to -80°C as supplied
1 month at 4°C after reconstitution with preservative
1 year at -20°C to -80°C after reconstitution
Expiration
See lot specific CoA

Hamster IL-4 Luminex Assay

Capture: Hamster IL-4 clone HM4-1C6 (Cat # M2035)
Detection: Hamster IL-4 clone HM4-3C11 (Cat # M2034)
Antigen: Recombinant Hamster IL-4, HEK expressed