Secreted protein acidic and rich in cysteine (SPARC), aka osteonectin, UniProt # P09486, is a glyocproetin secreted by a variety of cells and tumors. The biological functions of SPARC vary and include tissue remodeling as well as apoptosis. SPARC is considered a tumor inihbitor in various cancers such as breast, colorectal, pancreatic, and ovarian.
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